Gabapentin for Uremic Pruritus in Hemodialysis Patients: A Qualitative Systematic Review

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Gabapentin for uremic pruritus in hemodialysis patients: a qualitative systematic review.

PURPOSE OF THE REVIEW Uremic pruritus (UP) is a common discomfort of dialysis-dependent end-stage renal disease. Some studies suggest a neuropathic cause of UP. Gabapentin, an anticonvulsant, has shown promising results as an emerging drug to treat this condition. OBJECTIVE An updated qualitative systematic review was conducted to evaluate its efficacy and safety in hemodialysis patients. S...

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Topical Treatments for Uremic Pruritus in Hemodialysis Patients: A Systematic Review

Background & Objective: Pruritus is a common disruptive symptom in hemodialysis patients and those with chronic renal failure. Although pharmacological treatments could partially reduce pruritus in hemodialysis patients, the definitive treatment remains challenging in these patients. Several studies have been published in this regard, while no reviews have been focused on these articles. The pr...

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Comparison of Gabapentin and Ketotifen in Treatment of Uremic Pruritus in Hemodialysis Patients.

OBJECTIVES Uremic pruritus is a common problem in hemodialysis patients. Several treatments have been used for decreasing itching in these patients. Gabapentin and ketotifen are two drugs used for treating uremic patients. The aim of this study was to compare gabapentin and ketotifen in treatment of uremic pruritus in hemodialysis patients. METHODS In this double-blind randomized clinical tri...

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Effect of hemodialysis fluid cooling uremic pruritus in hemodialysis patients

Pruritus is a common problem in patients with chronic renal failure 25 to 35% before dialysis patients and 60 to 80% of dialysis patients may complain of pruritus (1). Despite advances in dialysis techniques and the treatment of uremic pruritus, it is remains an uncontrolled clinical problem in patients with chronic kidney disease (2). Results of a study have shown a 48% prevalence of pruritus ...

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Topical capsaicin therapy for uremic pruritus in patients on hemodialysis.

INTRODUCTION Pruritus is one of the common problems in patients on hemodialysis. There are several causes for pruritus, and different treatment modalities are applied to control it. The aim of this study was to evaluate the therapeutic effect of capsaicin on pruritus, compared with placebo, in patients on hemodialysis. MATERIALS AND METHODS This randomized double-blinded cross-over clinical t...

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ژورنال

عنوان ژورنال: Canadian Journal of Kidney Health and Disease

سال: 2016

ISSN: 2054-3581,2054-3581

DOI: 10.1186/s40697-016-0107-8